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A biodegradable tri‐component graft for anterior cruciate ligament reconstruction

Overview of attention for article published in Journal of Tissue Engineering and Regenerative Medicine, November 2014
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#8 of 1,089)
  • High Attention Score compared to outputs of the same age (99th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
16 news outlets
blogs
2 blogs
twitter
1 X user
patent
3 patents
facebook
3 Facebook pages
googleplus
1 Google+ user
reddit
1 Redditor

Readers on

mendeley
77 Mendeley
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Article details
Title
A biodegradable tri‐component graft for anterior cruciate ligament reconstruction
Published in
Journal of Tissue Engineering and Regenerative Medicine, November 2014
DOI 10.1002/term.1966
Pubmed ID
Authors
Abstract

Bone-patellar tendon-bone (BPTB) autografts are the gold standard for anterior cruciate ligament (ACL) reconstruction because the bony ends allow for superior healing and anchoring through bone-to-bone regeneration. However, the disadvantages of BPTB grafts include donor site morbidity and patellar rupture. In order to incorporate bone-to-bone healing without the risks associated with harvesting autogenous tissue, a biodegradable and synthetic tri-component graft was fabricated, consisting of porous poly(1,8-octanediol-co-citric acid)-hydroxyapatite nanocomposites (POC-HA) and poly(l-lactide) (PLL) braids. All regions of the tri-component graft were porous and the tensile properties were in the range of the native ACL. When these novel grafts were used to reconstruct the ACL of rabbits, all animals after 6 weeks were weight-bearing and showed good functionality. Histological assessment confirmed tissue infiltration throughout the entire scaffold and tissue ingrowth and interlocking within the bone tunnels, which is favourable for graft fixation. In conclusion, this pilot study suggests that a tri-component, biodegradable graft is a promising strategy to regenerate tissue types necessary for ACL tissue engineering, and provides a basis for developing an off-the-shelf graft for ACL repair. Copyright © 2014 John Wiley & Sons, Ltd.

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X Demographics

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Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
Spain 1 1%
Unknown 76 99%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Student > Ph. D. Student 17 22%
Student > Bachelor 12 16%
Researcher 9 12%
Student > Master 5 6%
Student > Doctoral Student 4 5%
Other 10 13%
Unknown 20 26%
Readers by discipline
Readers by discipline Count As %
Engineering 16 21%
Medicine and Dentistry 10 13%
Nursing and Health Professions 5 6%
Materials Science 4 5%
Biochemistry, Genetics and Molecular Biology 3 4%
Other 10 13%
Unknown 29 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 128. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 May 2024.
All research outputs
#391,144
of 32,106,825 outputs
Outputs from Journal of Tissue Engineering and Regenerative Medicine
#8
of 1,089 outputs
Outputs of similar age
#3,700
of 406,374 outputs
Outputs of similar age from Journal of Tissue Engineering and Regenerative Medicine
#1
of 13 outputs
Altmetric has tracked 32,106,825 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,089 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 406,374 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.