Differences in hypothalamic type 2 deiodinase ubiquitination explain localized sensitivity to thyroxine

Overview of attention for article published in Journal of Clinical Investigation, January 2015

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RT @MaryS58459511: 'patients on L-T4 monotherapy exhibit a relatively higher serum T4/T3 ratio' Why are doctors not concerned about this?…

'patients on L-T4 monotherapy exhibit a relatively higher serum T4/T3 ratio' Why are doctors not concerned about this? With T3 being the active hormone this should surely be a matter of concern.... https://t.co/Isg10SJo9H

@MeritTrust @NHSEngland "imbalance between T3 in hypothalamus & rest of body, TSH nomalised b4 T3 raised suff" https://t.co/4fRM2vX3cW

@GlasgowGhirl30 Enless titrating of doses is a waste of time GG. We need T3 and T4 to feel well. http://t.co/4fRM2vFslo Do u c an Endo?

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