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Determination of olopatadine in human tears by hydrophilic interaction liquid chromatographyMS/MS method

Overview of attention for article published in Bioanalysis, December 2017
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (72nd percentile)

Mentioned by

blogs
1 blog

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mendeley
8 Mendeley
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Title
Determination of olopatadine in human tears by hydrophilic interaction liquid chromatographyMS/MS method
Published in
Bioanalysis, December 2017
DOI 10.4155/bio-2017-0172
Pubmed ID
Authors

Jelena Maksi, Ana Staji, Miroslav Kneevi, Bojana Dai Krnjaja, Biljana JaniStojanovi, Mirjana Medenica

Abstract

The objective of the study was development of hydrophilic interaction liquid chromatography-ESI/MS/MS method for the determination of olopatadine in tear matrix. Separation was performed on Acquity BEH amide column (2.1 mm × 100 mm, 1.7 μm). The mobile phase was consisted of 0.1% formic acid in water and acetonitrile. Mianserin hydrochloride was implemented as an internal standard. The artificial tear fluid was used as matrix. The tear samples were collected using Schirmer test strips. For the optimization of ultra pressure liquid chromatography conditions, Box-Benhken design was utilized. The optimal values of the ion source and collision cell parameters were found. Quantification was performed in multiple reaction monitoring mode. The optimized method was fully validated. The proposed method was utilized for monitoring of olopatadine in human tear.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Other 1 13%
Student > Ph. D. Student 1 13%
Student > Master 1 13%
Researcher 1 13%
Professor > Associate Professor 1 13%
Other 0 0%
Unknown 3 38%
Readers by discipline Count As %
Medicine and Dentistry 2 25%
Pharmacology, Toxicology and Pharmaceutical Science 1 13%
Chemistry 1 13%
Agricultural and Biological Sciences 1 13%
Unknown 3 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2017.
All research outputs
#6,600,606
of 25,382,440 outputs
Outputs from Bioanalysis
#278
of 1,401 outputs
Outputs of similar age
#118,675
of 445,833 outputs
Outputs of similar age from Bioanalysis
#33
of 62 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,401 research outputs from this source. They receive a mean Attention Score of 3.3. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 445,833 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.