| Title |
Sudden Unexpected Death in Infancy: Biological Mechanisms
|
|---|---|
| Published in |
Paediatric Respiratory Reviews, September 2014
|
| DOI | 10.1016/j.prrv.2014.09.003 |
| Pubmed ID | |
| Authors | |
| Abstract |
Sudden unexpected death in infancy (SUDI) covers both explained and unexplained deaths. Unexplained cases or SIDS are likely to have multiple neural mechanisms contributing to the final event. The evidence ranges from subtle physiological signs related to autonomic control, to findings at autopsy of altered neurotransmitter systems, including the serotonergic system, a network that has an extensive homeostatic role in cardio-respiratory and thermoregulatory control. Processes may be altered by the vulnerability of the infant due to age, poor motor ability, or a genetic predisposition. The fatal event may occur in response to an environmental stress. A single final physiological route to death seems unlikely. An understanding of the reasons for explained SUDI also reminds us that a thorough investigation is required after each death occurs. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| South Africa | 1 | 2% |
| United States | 1 | 2% |
| Japan | 1 | 2% |
| Unknown | 58 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 9 | 15% |
| Student > Master | 8 | 13% |
| Student > Ph. D. Student | 4 | 7% |
| Researcher | 4 | 7% |
| Student > Postgraduate | 4 | 7% |
| Other | 15 | 25% |
| Unknown | 17 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 21 | 34% |
| Psychology | 4 | 7% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 5% |
| Social Sciences | 3 | 5% |
| Engineering | 3 | 5% |
| Other | 9 | 15% |
| Unknown | 18 | 30% |