@jjmerkin @doctorveera Yes, and I would add DEPICT to that list. I would say a necessary next step is to reference multiple traits, or focus on the strongest association per variant, rather than considering each gwas in isolation Then the enrichment ca…
The DEPICT paper (2015) https://t.co/gLiKRm0JBn uses the observation that the closest gene is usually the causal gene in part of its validation: https://t.co/Ypg1dt0FxM
RT @Eric_Fauman: Hi @LudeFranke I finally did an analysis with eqtlgen I've been wanting to do. The gene encoding the mRNA is the closest…
Hi @LudeFranke I finally did an analysis with eqtlgen I've been wanting to do. The gene encoding the mRNA is the closest to the lead cis eQTL SNP for that transcript 60% of the time, pretty close to what we see for pQTLs and mQTLs. Is this the correc…