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Silent Cerebral Infarction in East Asian vs. Non-Asian Atrial Fibrillation Patients ― Meta-Analysis ―

Overview of attention for article published in Circulation Journal, December 2017
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Title
Silent Cerebral Infarction in East Asian vs. Non-Asian Atrial Fibrillation Patients ― Meta-Analysis ―
Published in
Circulation Journal, December 2017
DOI 10.1253/circj.cj-17-1164
Pubmed ID
Authors

Keitaro Senoo, Yusuke Kondo, Yoshio Kobayashi, Gregory Yh Lip

Abstract

Atrial fibrillation (AF) is the most common arrhythmia in the ageing population in East Asia. Silent cerebral infarction (SCI) is defined as cerebral infarction in the absence of corresponding clinical symptoms, and is a highly prevalent and morbid condition in AF. SCI is increasingly being recognized as a risk factor for future stroke, which can lead to cognitive decline or dementia. The latter is an increasingly common health problem in East Asia.Methods and Results:We conducted a meta-analysis to compare the association of AF and SCI between East Asian and non-Asian patients. AF was associated with SCI in patients with no symptomatic stroke history (relative risk [RR], 2.24; 95% CI: 1.26-3.99, I2=83%; P=0.006) although the prevalence varied widely between studies (P for heterogeneity<0.001). In non-Asian patients, the prevalence of SCI in AF is higher than that in controls (RR, 1.85; 95% CI: 1.65-2.08, I2=17%; P<0.001). There was no significant racial difference between Asian and non-Asian studies (P=0.53). In East Asia, AF was significantly associated with SCI and no racial difference was seen between East Asian and non-Asian patients. The present findings offer clinicians new insights into the association between AF and SCI.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Other 3 10%
Student > Postgraduate 3 10%
Student > Bachelor 2 7%
Student > Ph. D. Student 2 7%
Researcher 2 7%
Other 6 20%
Unknown 12 40%
Readers by discipline Count As %
Medicine and Dentistry 9 30%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Psychology 1 3%
Nursing and Health Professions 1 3%
Other 2 7%
Unknown 15 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 December 2017.
All research outputs
#22,764,772
of 25,382,440 outputs
Outputs from Circulation Journal
#1,999
of 2,314 outputs
Outputs of similar age
#388,718
of 449,047 outputs
Outputs of similar age from Circulation Journal
#21
of 29 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
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