A comparison of the effects of endurance training on alternate days and on consecutive four days each week for eight weeks on the abundance of PGC-1α, CaMKII, NRF-1, mtTFA and COXIV proteins in rat skeletal muscle
Published in
Journal of Strength & Conditioning Research, November 2019
The aim of this study was to compare the effects of two training protocols, training on alternate days (A) or on consecutive four days followed by three days of rest in each week (C) for eight weeks, on selected proteins involved in the biogenesis and function of mitochondria in skeletal muscle. Eighty male SD rats were randomly allocated into 10 groups (n=8 each), including Pre and Post control groups, and A or C training groups with 8, 16, 24 and 32 training sessions, respectively. The vastus lateralis and soleus muscle samples were obtained 24 hours after the last training session, or at rest for the controls. The abundance of the proteins for PGC-1α, CaMKII, NRF-1, mtTFA and COXIV was analysed by Western blotting. Analysis of the results with two-way ANOVA showed no significant effect and interaction (training protocol by duration) in abundance of the proteins by the two protocols. However, fold changes normalized to control showed significant increases COXIV of the soleus muscle at most time points in both A and C training as indicated by Krumkal-Wallis H tests. There were significant correlations found between the abundance of the measured proteins of the vastus lateralis. The findings suggest that the two training protocols with the same intensity and total volume of work would not make a significant difference in respect of the changes in the targeted proteins. Alternative regulatory factors and the responses in different types of muscles to the training programs need to be examined in future research.
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 January 2020.
All research outputs
#23,913,139
of 34,151,039 outputs
Outputs from Journal of Strength & Conditioning Research
#5,998
of 7,345 outputs
Outputs of similar age
#273,549
of 413,580 outputs
Outputs of similar age from Journal of Strength & Conditioning Research
#113
of 140 outputs
Altmetric has tracked 34,151,039 research outputs across all sources so far. This one is in the 28th percentile – i.e., 28% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,345 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 21.1. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 413,580 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 31st percentile – i.e., 31% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 140 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.
