Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men

Overview of attention for article published in JCEM, January 2018

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Men’s propensity to aromatize testosterone into the estrogen is partially genetic: https://t.co/te082ozJRl

You've also bumped up against a limitation of the current experimental factor ontology. Many blood metabolites are not recorded as a "blood metabolite". E.g., androstenedione and estrone have both been reported at CYP11B2: https://t.co/naQQQXlM3V https:…

@mendel_random Presume you are referring to increased estrogen and its effect on bone mineral density as the plausible mechanism? (https://t.co/53WoteoCDY) Increased estrogen linked with earlier sexual maturity, and also lower BMD -> knee pain. Can't…

Genetic Determinants of Circulating Estrogen Levels and Evidence of a Causal Effect of Estradiol on Bone Density in Men Context: Serum estradiol (E2) and estrone (E1) levels exhibit substantial heritability.... https://t.co/r5KJ4pF6UJ

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