Science | 环化ADP核糖异构体的生成、化学结构与免疫信号传递
CN-Healthcare,
细菌、动物和植物等有机体必须防御自身以抵抗病原体，这些有机体的免疫信号通路中存在着同源的蛋白基序，TIR（Toll/interleukin-1 receptor）结构域则是代表性的一种。TIR结构域包含约150个氨基酸，广泛分布于动物、植物和细菌中，并通过自…
TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes
Overview of attention for article published in Current Biology, January 2018
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