| Title |
Complications of Massive Transfusion
|
|---|---|
| Published in |
CHEST, January 2010
|
| DOI | 10.1378/chest.09-0252 |
| Pubmed ID | |
| Authors | |
| Abstract |
Massive transfusion (MT) is a lifesaving treatment of hemorrhagic shock, but can be associated with significant complications. The lethal triad of acidosis, hypothermia, and coagulopathy associated with MT is associated with a high mortality rate. Other complications include hypothermia, acid/base derangements, electrolyte abnormalities (hypocalcemia, hypomagnesemia, hypokalemia, hyperkalemia), citrate toxicity, and transfusion-associated acute lung injury. Blood transfusion in trauma, surgery, and critical care has been identified as an independent predictor of multiple organ failure, systemic inflammatory response syndrome, increased infection, and increased mortality in multiple studies. Once definitive control of hemorrhage has been established, a restrictive approach to blood transfusion should be implemented to minimize further complications. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| South Africa | 3 | <1% |
| United Kingdom | 3 | <1% |
| United States | 2 | <1% |
| Japan | 2 | <1% |
| France | 1 | <1% |
| Spain | 1 | <1% |
| Germany | 1 | <1% |
| Czechia | 1 | <1% |
| Brazil | 1 | <1% |
| Other | 0 | 0% |
| Unknown | 369 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Postgraduate | 60 | 16% |
| Other | 56 | 15% |
| Researcher | 52 | 14% |
| Student > Master | 35 | 9% |
| Student > Bachelor | 27 | 7% |
| Other | 86 | 22% |
| Unknown | 68 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 242 | 63% |
| Agricultural and Biological Sciences | 11 | 3% |
| Biochemistry, Genetics and Molecular Biology | 10 | 3% |
| Nursing and Health Professions | 9 | 2% |
| Engineering | 5 | 1% |
| Other | 29 | 8% |
| Unknown | 78 | 20% |