Despite the effectiveness of total knee arthroplasty (TKA) for osteoarthritis (OA), up to 20% will report knee pain 1-year after surgery. One possible reason is the development of neuropathic pain before or after TKA.
To longitudinally describe suspected neuropathic pain in patients pre- and post-TKA and to explore relationships between pre-TKA suspected neuropathic pain and post-TKA outcomes.
Prospective observational study.
Participants were recruited from orthopedic surgery clinics prior to in-patient elective primary TKA.
Convenience sample of 135 patients were assessed for eligibility; 99 were enrolled and 74 completed the 6-month follow-up.
Participants completed the Self-Leeds Assessment of Neuropathic Symptoms and Signs (S-LANSS) and outcome measures at baseline (pre-TKA) and 1- and 6-months post-TKA by postal survey. Demographic variables included age, sex, and comorbidities. Descriptive statistics were calculated for the presence of suspected neuropathic pain at each assessment and course of outcomes for various suspected neuropathic pain trajectories. T-tests compared outcomes between those with and without suspected neuropathic pain at each assessment. Multiple linear regressions assessed the relationship between baseline suspected neuropathic pain and 6-month outcomes.
Intermittent and Constant Osteoarthritis Pain (ICOAP), Pain Catastrophizing Scale (PCS), and The Patient Health Questionnaire (PHQ-9) for depression.
Suspected neuropathic pain was present in 35.5% of pre-TKA patients, 39.0% at 1-month, and 23.6% at 6-months post-TKA. Those with suspected neuropathic pain had higher scores for ICOAP total pain (p = .05), pain catastrophizing (p < .01), and depression (p < .01) at each assessment. After adjusting for potential confounding, pre-TKA suspected neuropathic pain did not predict ICOAP total pain or PHQ-9 depression scores at 6-months.
Although 14% of individuals with knee OA had suspected neuropathic pain that persisted 6-months post-TKA and those with suspected neuropathic pain had higher levels of pain, catastrophizing, and depression, the clinical identification of neuropathic pain remains enigmatic. Preoperative suspected neuropathic pain, as measured by S-LANSS, may have limited prognostic value for post-TKA outcomes.
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2018.
All research outputs
#10,450,042
of 32,674,756 outputs
Outputs from PM&R
#794
of 1,972 outputs
Outputs of similar age
#162,556
of 486,853 outputs
Outputs of similar age from PM&R
#19
of 47 outputs
Altmetric has tracked 32,674,756 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 1,972 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.3. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 486,853 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.
