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@DrPaulyDeSantis @Aiims1742 @MDAndersonNews @UTSWNews @PanCAN Betalapachone is bioactivated by an enzyme nqo1 (present on tumor cell)-> leading to dna damage/cessation of metabolism and synergy w chemo https://t.co/HIRL8wXb2J
Using a novel NQO1 bioactivatable drug, beta‐lapachone (ARQ761), to enhance chemotherapeutic effects by metabolic modulation in pancreatic cancer
Overview of attention for article published in Journal of Surgical Oncology, March 2017