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Consequences of an early catheter‐based intervention on pulmonary artery growth and right ventricular myocardial function in a pig model of pulmonary artery stenosis

Overview of attention for article published in Catheterization and Cardiovascular Interventions (Formerly Catheterization and Cardiovascular Diagnosis), March 2018
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Article details
Title
Consequences of an early catheter‐based intervention on pulmonary artery growth and right ventricular myocardial function in a pig model of pulmonary artery stenosis
Published in
Catheterization and Cardiovascular Interventions (Formerly Catheterization and Cardiovascular Diagnosis), March 2018
DOI 10.1002/ccd.27593
Pubmed ID
Authors
Abstract

To determine the consequences of an early catheter-based intervention on pulmonary artery (PA) growth and right ventricular (RV) myocardial function in an animal model of branch PA stenosis. Acute results and safety profiles of deliberate stent fracture within the pulmonary vasculature have been demonstrated. The long-term impact of early stent intervention and deliberate stent fracture on PA growth and myocardial function is not understood. Implantation of small diameter stents was performed in a pig model of left PA stenosis at 6 weeks (10 kg) followed by dilations at 10 (35 kg) and 18 weeks (65 kg) with intent to fracture and implant large diameter stents. Hemodynamics, RV contractility, and 2D/3D angiography were performed with each intervention. The heart and pulmonary vasculature were histologically assessed. Stent fracture occurred in 9/12 and implantation of large diameter stents was successful in 10/12 animals with no PA aneurysms or dissections. The final stented PA segment and distal left PA branch origins equaled the corresponding PA diameters of sham controls. Growth of left PA immediately beyond the stent was limited and there was diffuse fibro-intimal proliferation within the distal left and right PA. RV contractility was diminished in the intervention group and the response to dobutamine occurred uniquely via increases in heart rate. Early stent intervention in this surgically created PA stenosis model was associated with improved growth of the distal PA vasculature but additional investigation of PA vessel physiology and impact on the developing heart are needed.

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The data shown below were compiled from readership statistics for 10 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
Unknown 10 100%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Student > Ph. D. Student 2 20%
Researcher 2 20%
Student > Bachelor 1 10%
Unknown 5 50%
Readers by discipline
Readers by discipline Count As %
Medicine and Dentistry 3 30%
Engineering 2 20%
Unknown 5 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 January 2022.
All research outputs
#28,671,300
of 34,447,360 outputs
Outputs from Catheterization and Cardiovascular Interventions (Formerly Catheterization and Cardiovascular Diagnosis)
#4,182
of 4,722 outputs
Outputs of similar age
#301,534
of 372,133 outputs
Outputs of similar age from Catheterization and Cardiovascular Interventions (Formerly Catheterization and Cardiovascular Diagnosis)
#43
of 51 outputs
Altmetric has tracked 34,447,360 research outputs across all sources so far. This one is in the 9th percentile – i.e., 9% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,722 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.4. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 372,133 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.