Mutations Conferring Increased Sensitivity to Tripartite Motif 22 Restriction Accumulated Progressively in the Nucleoprotein of Seasonal Influenza A (H1N1) Viruses between 1918 and 2009

Long-term circulation of seasonal influenza A viruses in the human population resulted in progressive acquisition of increased sensitivity to a component of the innate immune response: the type I IFN-inducible TRIM22 https://t.co/ceNzrqetDc @ASMicrobiol…