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Chlorine dioxide is a superior disinfectant against multi-drug resistant Staphylococcus aureus, Pseudomonas aeruginosa and Acinetobacter baumannii

Overview of attention for article published in Japanese Journal of Infectious Diseases, January 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#15 of 893)
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

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Title
Chlorine dioxide is a superior disinfectant against multi-drug resistant Staphylococcus aureus, Pseudomonas aeruginosa and Acinetobacter baumannii
Published in
Japanese Journal of Infectious Diseases, January 2015
DOI 10.7883/yoken.jjid.2014.294
Pubmed ID
Authors

Atsushi Hinenoya, Sharda Prasad Awasthi, Noritomo Yasuda, Ayaka Shima, Hirofumi Morino, Tomoko Koizumi, Toshiaki Fukuda, Takanori Miura, Takashi Shibata, Shinji Yamasaki

Abstract

In this study, we evaluated the antibacterial activity of chlorine dioxide (ClO2) compared with sodium hypochlorite (NaClO) on various multidrug-resistant strains in the presence of bovine serum albumin and sheep erythrocytes to mimic the frequent blood contamination in clinical environment. The 3 most important species causing nosocomial infections, i.e., methicillin-resistant Staphylococcus aureus (MRSA), multidrug-resistant Pseudomonas aeruginosa (MDRP) and multidrug-resistant Acinetobacter baumannii (MDRA) were evaluated, with 3 representative strains from each. At a 10 ppm-concentration, ClO2 drastically reduced the number of all MDRP and MDRA, and 2 out of 3 MRSA strains, but NaClO was unable to cause any remarkable attenuation for any of the 9 strains tested in 60 seconds. Increased concentration of 100 ppm enabled ClO2 to completely kill MRSA strains, whereas NaClO failed to significantly lower the number of 2 MRSA and 1 MDRA strains. A time-course experiment demonstrated that, within 15 seconds, 100 ppm of ClO2 could kill completely all tested strains but NaClO at this concentration failed to do so. Together, these data suggest that ClO2 is more effective than NaClO against MRSA, MDRP and MDRA, and 100 ppm could be a practical concentration of ClO2 against these multidrug-resistant strains, which may cause fatal nosocomial infections.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 50 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 14%
Researcher 7 14%
Student > Master 5 10%
Student > Ph. D. Student 4 8%
Professor 4 8%
Other 8 16%
Unknown 15 30%
Readers by discipline Count As %
Immunology and Microbiology 6 12%
Agricultural and Biological Sciences 6 12%
Biochemistry, Genetics and Molecular Biology 5 10%
Engineering 5 10%
Medicine and Dentistry 3 6%
Other 9 18%
Unknown 16 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 July 2022.
All research outputs
#1,750,911
of 25,774,185 outputs
Outputs from Japanese Journal of Infectious Diseases
#15
of 893 outputs
Outputs of similar age
#23,473
of 362,139 outputs
Outputs of similar age from Japanese Journal of Infectious Diseases
#2
of 12 outputs
Altmetric has tracked 25,774,185 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 893 research outputs from this source. They receive a mean Attention Score of 3.3. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 362,139 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.