| Title |
Dysbindin (DTNBP1) variants are associated with hallucinations in schizophrenia
|
|---|---|
| Published in |
European Psychiatry, April 2020
|
| DOI | 10.1016/j.eurpsy.2015.01.008 |
| Pubmed ID | |
| Authors | |
| Abstract |
Dystrobrevin binding protein 1 (DTNBP1) is a schizophrenia susceptibility gene involved with neurotransmission regulation (especially dopamine and glutamate) and neurodevelopment. The gene is known to be associated with cognitive deficit phenotypes within schizophrenia. In our previous studies, DTNBP1 was found associated not only with schizophrenia but with other psychiatric disorders including psychotic depression, post-traumatic stress disorder, nicotine dependence and opiate dependence. These findings suggest that DNTBP1 may be involved in pathways that lead to multiple psychiatric phenotypes. In this study, we explored the association between DTNBP1 SNPs (single nucleotide polymorphisms) and multiple psychiatric phenotypes included in the Diagnostic Interview of Psychosis (DIP). |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Denmark | 1 | <1% |
| Unknown | 111 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 22 | 19% |
| Researcher | 14 | 12% |
| Student > Bachelor | 12 | 11% |
| Student > Ph. D. Student | 10 | 9% |
| Student > Postgraduate | 7 | 6% |
| Other | 17 | 15% |
| Unknown | 31 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 26 | 23% |
| Medicine and Dentistry | 13 | 12% |
| Neuroscience | 10 | 9% |
| Agricultural and Biological Sciences | 7 | 6% |
| Biochemistry, Genetics and Molecular Biology | 6 | 5% |
| Other | 14 | 12% |
| Unknown | 37 | 33% |