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Efficacy of fentanyl transdermal patch in pain control after lower third molar surgery: A preliminary study

Overview of attention for article published in Medicina Oral Patología Oral y Cirugia Bucal, September 2016
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Title
Efficacy of fentanyl transdermal patch in pain control after lower third molar surgery: A preliminary study
Published in
Medicina Oral Patología Oral y Cirugia Bucal, September 2016
DOI 10.4317/medoral.21161
Pubmed ID
Authors

Vladimir S. Todorovic, Miroslav Vasovic, Miroslav Andric, Ljubomir Todorovic, Vladimir Kokovic

Abstract

Surgical removal of impacted lower third molars is a common oral surgical procedure, generally followed by moderate to severe postoperative pain. Transdermal drug delivery as a concept offers interesting possibilities for postoperative pain control. The aim of this study was to evaluate the efficacy of transdermal system with fentanyl in relieving pain following impacted lower third molar surgery. Seventeen patients with bilateral impacted lower third molars were included in this preliminary study. For postoperative pain control, patients randomly received a fentanyl patch plus placebo tablet after the first operation and regular (placebo) patch and an analgesic, after the second operation. Analgesia was evaluated during first 24 hours postoperatively according to patients' reports about time of first pain appearance and additional analgesic consumption. Pain severity was rated using a 10 cm long visual analogue scale (VAS). Intensity of postoperative pain and postoperative analgesic consumption were significantly lower after the Fentanyl Transdermal System (FTS) was applied (p<0.05). Duration of postoperative analgesia was significantly higher with FTS when compared to control treatment (p<0.05). Based on the results of this preliminary study, transdermal system with fentanyl significantly reduced postoperative pain after third molar surgery.

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The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 56 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 20%
Student > Ph. D. Student 4 7%
Student > Bachelor 3 5%
Researcher 3 5%
Professor > Associate Professor 3 5%
Other 8 14%
Unknown 24 43%
Readers by discipline Count As %
Medicine and Dentistry 26 46%
Unspecified 1 2%
Nursing and Health Professions 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Computer Science 1 2%
Other 1 2%
Unknown 25 45%