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Potentiation of GABAA Receptors Expressed in Xenopus Oocytes by Perfume and Phytoncid

Overview of attention for article published in Nippon Nōgeikagaku Kaishi, May 2014
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Title
Potentiation of GABAA Receptors Expressed in Xenopus Oocytes by Perfume and Phytoncid
Published in
Nippon Nōgeikagaku Kaishi, May 2014
DOI 10.1271/bbb.63.743
Pubmed ID
Authors

Hitoshi AOSHIMA, Koutaro HAMAMOTO

Abstract

To study the effects of perfume and phytoncid on GABAA receptors, ionotropic GABAA receptors were expressed in Xenopus oocytes by injecting mRNAs that had been prepared from rat whole brain. Essential oil, perfume and such phytoncid as leaf alcohol, hinokitiol, pinene, eugenol, citronellol and citronellal potentiated the response in the presence of GABA at low concentrations (10 and 30 microM), possibly because they bound to the potentiation-site in GABAA receptors and increased the affinity of GABA to the receptors. Since it is known that the potentiation of GABAA receptors by benzodiazepine, barbiturate, steroids and anesthetics induces the anxiolytic, anticonvulsant and sedative activity or anesthetic effect, these results suggest the possibility that the intake of perfume or phytoncid through the lungs, the skin or the intestines modulates the neural transmission in the brain through ionotropic GABAA receptors and changes the frame of the human mind, as alcohol or tobacco does.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 1%
Italy 1 1%
Unknown 78 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 15 19%
Researcher 7 9%
Other 7 9%
Student > Master 7 9%
Student > Ph. D. Student 6 8%
Other 12 15%
Unknown 26 33%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 23%
Medicine and Dentistry 9 11%
Pharmacology, Toxicology and Pharmaceutical Science 5 6%
Nursing and Health Professions 3 4%
Biochemistry, Genetics and Molecular Biology 3 4%
Other 14 18%
Unknown 28 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 April 2018.
All research outputs
#23,195,360
of 25,850,671 outputs
Outputs from Nippon Nōgeikagaku Kaishi
#6,820
of 7,190 outputs
Outputs of similar age
#208,457
of 240,956 outputs
Outputs of similar age from Nippon Nōgeikagaku Kaishi
#2,736
of 2,823 outputs
Altmetric has tracked 25,850,671 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,190 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,956 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2,823 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.