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Aging induced cortical drive alterations during sleep in rats

Overview of attention for article published in Mechanisms of Ageing & Development, March 2015
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Title
Aging induced cortical drive alterations during sleep in rats
Published in
Mechanisms of Ageing & Development, March 2015
DOI 10.1016/j.mad.2015.03.002
Pubmed ID
Authors

Jelena Ciric, Katarina Lazic, Jelena Petrovic, Aleksandar Kalauzi, Jasna Saponjic

Abstract

We followed the impact of healthy aging on cortical drive during sleep in rats by using the corticomuscular coherence (CMC). We employed the chronic electrodes implantation for sleep recording in adult, male Wistar rats, and followed the aging impact during sleep from 3 to 5.5 months age. We have analyzed the sleep/wake states architecture, and the sleep/wake state related EEG microstructure and CMCs. We evidenced the topographically distinct impact of aging on sleep/wake states architecture within the sensorimotor (SMCx) vs. motor cortex (MCx) from 4.5 to 5.5 months age. Healthy aging consistently altered only the SMCx sleep/wake states architecture, and increased the delta and beta CMCs through both cortical drives during Wake, but only through the MCx drive during REM. According to the delta and beta CMCs values, aging impact through the SMCx drive was opposite, but it was convergent through the MCx drive during Wake vs. REM, and there was a dual and inverse mode for the motor control during REM.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 24 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Serbia 2 8%
Unknown 22 92%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 21%
Student > Master 3 13%
Student > Bachelor 3 13%
Student > Ph. D. Student 3 13%
Student > Doctoral Student 2 8%
Other 6 25%
Unknown 2 8%
Readers by discipline Count As %
Neuroscience 6 25%
Medicine and Dentistry 6 25%
Biochemistry, Genetics and Molecular Biology 3 13%
Agricultural and Biological Sciences 3 13%
Psychology 2 8%
Other 2 8%
Unknown 2 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 March 2015.
All research outputs
#22,760,732
of 25,374,917 outputs
Outputs from Mechanisms of Ageing & Development
#1,373
of 1,494 outputs
Outputs of similar age
#235,567
of 274,386 outputs
Outputs of similar age from Mechanisms of Ageing & Development
#14
of 15 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,494 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.4. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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