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The catecholamine system in health and disease

Overview of attention for article published in Proceedings of the Japan Academy, Series B: Physical and Biological Sciences, January 2007
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Title
The catecholamine system in health and disease
Published in
Proceedings of the Japan Academy, Series B: Physical and Biological Sciences, January 2007
DOI 10.2183/pjab.82.388
Pubmed ID
Authors

Toshiharu Nagatsu

Abstract

Catecholamines [dopamine, noradrenaline (norepinephrine), and adrenaline (epinephrine); CAs] are neurotransmitters in the central and peripheral nervous systems as well as hormones in the endocrine system. CAs in the brain play a central role in versatile functions as slow-acting neurotransmitters functioning in synaptic neurotransmission, modulating the effects of fast-acting neurotransmitters such as glutamate and γ-aminobutyric acid (GABA). In this review, I focus on recent advances in the biochemistry and molecular biology of the CA system in humans in health and disease, especially in neuropsychiatric diseases such as Parkinson's disease (PD), in relation to the biosynthesis of CAs regulated by a pteridine-dependent monooxygenase, tyrosine 3-monooxygenase (tyrosine hydroxylase, TH) and its pteridine cofactor, tetrahydrobiopterin (BH4).

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 91 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 91 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 17 19%
Student > Ph. D. Student 15 16%
Student > Master 10 11%
Unspecified 6 7%
Researcher 5 5%
Other 11 12%
Unknown 27 30%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 17 19%
Agricultural and Biological Sciences 10 11%
Unspecified 6 7%
Medicine and Dentistry 6 7%
Neuroscience 5 5%
Other 19 21%
Unknown 28 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 August 2023.
All research outputs
#15,484,736
of 25,850,671 outputs
Outputs from Proceedings of the Japan Academy, Series B: Physical and Biological Sciences
#283
of 422 outputs
Outputs of similar age
#146,894
of 173,746 outputs
Outputs of similar age from Proceedings of the Japan Academy, Series B: Physical and Biological Sciences
#8
of 9 outputs
Altmetric has tracked 25,850,671 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 422 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 41.9. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 173,746 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one.