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Inhalation Anesthesia Is Preferable for Recording Rat Cardiac Function Using an Electrocardiogram

Overview of attention for article published in Biological and Pharmaceutical Bulletin, January 2014
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Title
Inhalation Anesthesia Is Preferable for Recording Rat Cardiac Function Using an Electrocardiogram
Published in
Biological and Pharmaceutical Bulletin, January 2014
DOI 10.1248/bpb.b14-00012
Pubmed ID
Authors

Manabu Murakami, Hidetoshi Niwa, Tetsuya Kushikata, Hiroyuki Watanabe, Kazuyoshi Hirota, Kyoichi Ono, Takayoshi Ohba

Abstract

The effects of inhalation anesthesia (2% isoflurane, sevoflurane, or enflurane) and intraperitoneal anesthesia with pentobarbital (65 mg/kg) were compared in rats using an electrocardiogram (ECG) and determination of blood oxygen saturation (SPO2) levels. Following inhalation anesthesia, heart rate (HR) and SPO2 were acceptable while pentobarbital anesthesia decreased HR and SPO2 significantly. This indicates that inhalation anesthesia is more preferable than pentobarbital anesthesia when evaluating cardiovascular factors. Additionally, pentobarbital significantly increased HR variability (HRV), suggesting a regulatory effect of pentobarbital on the autonomic nervous system, and resulted in a decreased response of the baro-reflex system. Propranolol or atropine had limited effects on ECG recording following pentobarbital anesthesia. Taken together, these data suggest that inhalation anesthesia is suitable for conducting hemodynamic analyses in the rat.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 17%
Student > Master 6 15%
Student > Bachelor 5 12%
Professor > Associate Professor 5 12%
Student > Ph. D. Student 4 10%
Other 7 17%
Unknown 7 17%
Readers by discipline Count As %
Medicine and Dentistry 13 32%
Agricultural and Biological Sciences 8 20%
Pharmacology, Toxicology and Pharmaceutical Science 5 12%
Engineering 2 5%
Sports and Recreations 1 2%
Other 3 7%
Unknown 9 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2014.
All research outputs
#20,656,791
of 25,380,192 outputs
Outputs from Biological and Pharmaceutical Bulletin
#2,588
of 3,271 outputs
Outputs of similar age
#238,286
of 312,604 outputs
Outputs of similar age from Biological and Pharmaceutical Bulletin
#58
of 79 outputs
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So far Altmetric has tracked 3,271 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
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