| Title |
What is the evidence for a role for diet and nutrition in osteoarthritis?
|
|---|---|
| Published in |
Rheumatology, April 2018
|
| DOI | 10.1093/rheumatology/key011 |
| Pubmed ID | |
| Authors |
Sally Thomas, Heather Browne, Ali Mobasheri, Margaret P Rayman |
| Abstract |
As current treatment options in OA are very limited, OA patients would benefit greatly from some ability to self-manage their condition. Since diet may potentially affect OA, we reviewed the literature on the relationship between nutrition and OA risk or progression, aiming to provide guidance for clinicians. For overweight/obese patients, weight reduction, ideally incorporating exercise, is paramount. The association between metabolic syndrome, type-2 diabetes and OA risk or progression may partly explain the apparent benefit of dietary-lipid modification resulting from increased consumption of long-chain omega-3 fatty-acids from oily fish/fish oil supplements. A strong association between OA and raised serum cholesterol together with clinical effects in statin users suggests a potential benefit of reduction of cholesterol by dietary means. Patients should ensure that they meet the recommended intakes for micronutrients such as vitamin K, which has a role in bone/cartilage mineralization. Evidence for a role of vitamin D supplementation in OA is unconvincing. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 16 | 27% |
| United States | 7 | 12% |
| South Africa | 3 | 5% |
| Canada | 3 | 5% |
| Japan | 3 | 5% |
| Australia | 2 | 3% |
| Germany | 2 | 3% |
| Spain | 2 | 3% |
| Hungary | 1 | 2% |
| Other | 6 | 10% |
| Unknown | 15 | 25% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 46 | 77% |
| Practitioners (doctors, other healthcare professionals) | 9 | 15% |
| Scientists | 3 | 5% |
| Science communicators (journalists, bloggers, editors) | 1 | 2% |
| Unknown | 1 | 2% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 514 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 90 | 18% |
| Student > Master | 66 | 13% |
| Researcher | 37 | 7% |
| Other | 24 | 5% |
| Student > Doctoral Student | 23 | 4% |
| Other | 68 | 13% |
| Unknown | 206 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Nursing and Health Professions | 101 | 20% |
| Medicine and Dentistry | 86 | 17% |
| Biochemistry, Genetics and Molecular Biology | 36 | 7% |
| Agricultural and Biological Sciences | 18 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 12 | 2% |
| Other | 39 | 8% |
| Unknown | 222 | 43% |