Paracetamol has the potential to also promote weight gain by indirect activation of cannabinoid receptors. The association between paracetamol use in the first 12 months of life or recent high use and BMI in children and adolescents was investigated.
Paracetamol use in the first 12 months of life (reported by parents/guardians of 6- and 7-year-olds) or in the past 12 months (reported by parents/guardians of 6- and 7-year-olds or self-reported by adolescents aged 13-14) was examined in relation to BMI in a large multicentre cross-sectional study (2000-2003). Linear regression results were adjusted for whether height and weight were reported or measured, age, sex, country gross national income, study centre, maternal smoking, and recent wheeze.
Data were available from 76,216 children (18 countries) and 188,469 adolescents (35 countries). BMI was +0.07 kg/m(2) higher in children with early life paracetamol exposure, from affluent countries only. Frequent recent paracetamol use was associated with higher BMI (+0.17 kg/m(2) , P < 0.0001) among adolescents from affluent countries only, but not in children (P = 0.41).
Paracetamol may be causally related to increased BMI; alternatively, the association may be explained by lifestyle or other factors that correlate with paracetamol use in affluent countries.
Pharmacology, Toxicology and Pharmaceutical Science
4
4%
Agricultural and Biological Sciences
3
3%
Biochemistry, Genetics and Molecular Biology
2
2%
Other
9
10%
Unknown
37
40%
Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2015.
All research outputs
#16,046,765
of 25,371,288 outputs
Outputs from Obesity
#3,847
of 5,065 outputs
Outputs of similar age
#151,159
of 278,948 outputs
Outputs of similar age from Obesity
#57
of 73 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,065 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 35.6. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,948 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.
