Asymmetric distribution and spatial switching of dynein activity generates ciliary motility

Overview of attention for article published in Science, April 2018

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@EM_mikestrauss @TheVillaLab @RuiZhangWUSTL @micromotility Well😜, to continue that car analogy... a car has a motor, transmission, computer, etc. that could function outside the integrated whole. So a car isn't a machine? Axonemal dyneins function collec…

SH: Goal is to model cells or large machines e.g. Axoneme and beating flagella (https://t.co/Hih4p4mOXB). But how do we bridge from the atomic level to the micrometer scale? There are 10^14 atoms in an eukaryotic cell. Is MD really the answer? No! 1/

Targeted dynein inhibition generates flagellar beating published as: https://t.co/kkcVp26bBn @sciencemagazine #biorxiv

Amazing! The animation at the end is everything! Asymmetric distribution and spatial switching of dynein activity generates ciliary motility https://t.co/YwdrTig1Ql

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