Mechanism that Helps Leukaemia Cells Resist Glucocorticoids Identified
Scicasts,
Memphis, TN (Scicasts) — Researchers led by St. Jude Children’s Research Hospital scientists have identified a mechanism that…
NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells
Bioportfolio,
William Evans and colleagues find that the proinflammatory genes CASP1 and NLRP3 are expressed at higher levels in primary…
Discovery could help reverse glucocorticoid resistance in some young leukemia patients
MedicalXpress,
Researchers led by St. Jude Children's Research Hospital scientists have identified a mechanism that helps leukemia cells…