Are your covariates under control? How normalization can re-introduce covariate effects

Overview of attention for article published in European Journal of Human Genetics, April 2018

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Are Your Covariates Under Control? How Normalization Can Re-introduce Covariate Effects published as: https://t.co/5ASfqegfT9 @eshgsociety #biorxiv

RT briandavidearp: RT CristianPattaro: Apply rank-based inverse normal transformation before adjusting for covariates not on residuals: risk to re-introduce covariate effects Important piece by O. Pain, F. Dudbridge and Gelironald about #GWAS https://t.…

RT @NPirastu: We have been struggling with getting rid of population structure in GWAS and it is showing especially in PGRS. Could the rank…

Good to know... suggestion to use inverse normal transformation prior to residualizing as opposed to on residuals themselves.

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