The reaction mechanism for self-splicing introns requires the existence of a 5' exon binding site on the intron. Experimental evidence is now presented consistent with the existence of such a binding site by demonstrating efficient and accurate trans-self-splicing of a yeast mitochondrial group II intron. Partial and complete trans-splicing reactions take place in the absence of branch formation, part of the usual pathway of nuclear splicing and group II self-splicing. In addition to indicating the existence of a 5' exon binding site on the intron, the results have mechanistic implications for group II self-splicing and perhaps for nuclear splicing as well.
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 March 2012.
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#7,557,454
of 23,052,509 outputs
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#48,243
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Outputs of similar age
#8,685
of 45,374 outputs
Outputs of similar age from Science
#59
of 122 outputs
Altmetric has tracked 23,052,509 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 78,178 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 62.5. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
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