| Title |
Long-term structural changes after mTBI and their relation to post-concussion symptoms
|
|---|---|
| Published in |
Brain Injury, June 2015
|
| DOI | 10.3109/02699052.2015.1035334 |
| Pubmed ID | |
| Authors | |
| Abstract |
To investigate sustained structural changes in the long-term (>1 year) after mild traumatic brain injury (mTBI) and their relationship to ongoing post-concussion syndrome (PCS). Morphological and structural connectivity magnetic resonance imaging (MRI) data were acquired from 16 participants with mTBI and nine participants without previous head injury. Participants with mTBI had less prefrontal grey matter and lower fractional anisotropy (FA) in the anterior corona radiata and internal capsule. Furthermore, PCS severity was associated with less parietal lobe grey matter and lower FA in the corpus callosum. There is evidence for both white and grey matter damage in participants with mTBI over 1 year after injury. Furthermore, these structural changes are greater in those that report more PCS symptoms, suggesting a neurophysiological basis for these persistent symptoms. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | 67% |
| Canada | 1 | 17% |
| Unknown | 1 | 17% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 100% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Unknown | 147 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 14% |
| Student > Master | 20 | 13% |
| Student > Doctoral Student | 14 | 9% |
| Student > Bachelor | 12 | 8% |
| Other | 11 | 7% |
| Other | 29 | 19% |
| Unknown | 42 | 28% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 29 | 19% |
| Medicine and Dentistry | 24 | 16% |
| Psychology | 21 | 14% |
| Nursing and Health Professions | 7 | 5% |
| Sports and Recreations | 6 | 4% |
| Other | 14 | 9% |
| Unknown | 48 | 32% |