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Structure-activity relationship analysis of substituted 4-quinolinamines, antagonists of immunostimulatory CpG-oligodeoxynucleotides

Overview of attention for article published in Bioorganic & Medicinal Chemistry Letters, July 1999
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

patent
14 patents

Readers on

mendeley
12 Mendeley
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Article details
Title
Structure-activity relationship analysis of substituted 4-quinolinamines, antagonists of immunostimulatory CpG-oligodeoxynucleotides
Published in
Bioorganic & Medicinal Chemistry Letters, July 1999
DOI 10.1016/s0960-894x(99)00291-7
Pubmed ID
Authors
Abstract

On the basis of a systematic SAR analysis of substituted quinolines, a derivative 32 was synthesized that shows half-maximal inhibition of the immunostimulatory effect of CpG-oligodeoxynucleotides in vitro at the concentration of 0.24 nM.

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Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.
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Geographical breakdown

Geographical breakdown
Country Count As %
India 1 8%
Ireland 1 8%
Unknown 10 83%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Researcher 4 33%
Student > Ph. D. Student 4 33%
Student > Doctoral Student 2 17%
Professor > Associate Professor 1 8%
Unknown 1 8%
Readers by discipline
Readers by discipline Count As %
Chemistry 4 33%
Agricultural and Biological Sciences 3 25%
Chemical Engineering 1 8%
Biochemistry, Genetics and Molecular Biology 1 8%
Immunology and Microbiology 1 8%
Other 1 8%
Unknown 1 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 August 2023.
All research outputs
#2,943,586
of 33,493,714 outputs
Outputs from Bioorganic & Medicinal Chemistry Letters
#505
of 16,687 outputs
Outputs of similar age
#2,335
of 49,714 outputs
Outputs of similar age from Bioorganic & Medicinal Chemistry Letters
#5
of 121 outputs
Altmetric has tracked 33,493,714 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 16,687 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 49,714 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 121 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.