| Title |
Relapsing and remitting human immunodeficiency virus—associated leukoencephalomyelopathy
|
|---|---|
| Published in |
Annals of Neurology, October 2004
|
| DOI | 10.1002/ana.410310107 |
| Pubmed ID | |
| Authors |
Joseph R. Berger, Carlo Tornatore, Eugene O. Major, Jocelyn Bruce, Paul Shapshak, Masaru Yoshioka, Sydney Houff, William Sheremata, Gerald F. Horton, Howard Landy |
| Abstract |
We describe a 33-year-old homosexual man with a steroid-responsive, remitting and relapsing leukoencephalopathy associated with recent human immunodeficiency virus type 1 (HIV-1) seroconversion. Biopsy of a parieto-occipital lesion revealed demyelination and astrogliosis with focal necrosis. Detailed investigations demonstrated no pathogens in the brain other than HIV-1. This patient illustrates that a neurological disorder clinically indistinguishable from multiple sclerosis may be the presenting manifestation of HIV-1 infection and may occur in the absence of clinically significant immunosuppression. |
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Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 18 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 2 | 11% |
| Professor | 2 | 11% |
| Student > Master | 2 | 11% |
| Student > Doctoral Student | 1 | 6% |
| Student > Bachelor | 1 | 6% |
| Other | 3 | 17% |
| Unknown | 7 | 39% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 6 | 33% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 6% |
| Nursing and Health Professions | 1 | 6% |
| Immunology and Microbiology | 1 | 6% |
| Psychology | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 7 | 39% |