Toward a foundation model of causal cell and tissue biology with a Perturbation Cell and Tissue Atlas
Cell,
This Review describes experimental platforms for high-throughput, multi-modal perturbation screens and associated computational…
Positive selection CRISPR screens reveal a druggable pocket in an oligosaccharyltransferase required for inflammatory signaling to NF-κB
Cell,
Innovative approaches identify druggable glycosylation processes that regulate TLR4-mediated activation of the pro-inflammatory…
How to Design Your gRNA for CRISPR Genome Editing
Addgene,
This post was contributed by guest blogger, Addgene Advisory Board member, and Associate Director of the Genetic…