Reduced Right Ventrolateral Prefrontal Cortex Activity While Inhibiting Positive Affect Is Associated with Improvement in Hedonic Capacity After 8 Weeks of Antidepressant Treatment in Major Depressive Disorder
Anhedonia, a reduced ability to experience pleasure, is a chief symptom of major depressive disorder and is related to reduced frontostriatal connectivity when attempting to upregulate positive emotion. The present study examined another facet of positive emotion regulation associated with anhedonia-namely, the downregulation of positive affect-and its relation to prefrontal cortex (PFC) activity.
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 June 2021.
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#22,699,295
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#5,914
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#124,218
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Outputs of similar age from Biological Psychiatry
#49
of 74 outputs
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