Identification of Genetic Factors that Modify Clinical Onset of Huntington’s Disease

Overview of attention for article published in Cell, July 2015

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@mbeisen GWAS in Huntington’s disease identified genetic modifiers of disease progression which are now under development. DNA repair enzymes. https://t.co/ZaIMtvsa4v

@murphyslaw1987 @ciphergoth @ProfSimonFisher but both were born with single gene mutation and experienced disease there are definitely genetic modifiers of this expansion and onset https://t.co/n0wdED3nUB but you still need to inherit the expanded C…

13/ Is it more than just the repeats...? A study shows 3 loci are highly linked to disease onset, affecting the disease before symptoms show ⤵️ 1⃣Chromosome 15: earlier by 6 years 2⃣Chromosome 15: delayed by 1.5 years 3⃣Chromosome 8: earlier by 1.5 years …

links to 2 articles: https://t.co/OPMerKiOih https://t.co/SBry6z5LEj

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