| Title |
Pathophysiology Review
|
|---|---|
| Published in |
Clinical nurse specialist, July 2018
|
| DOI | 10.1097/nur.0000000000000384 |
| Pubmed ID | |
| Authors | |
| Abstract |
Delirium affects 70% to 80% of intensive care unit patients and is associated with a 10-fold increase in rates of cognitive impairment at discharge and a 3-fold increase in mortality rates. Estimated costs are $152 billion in Medicare charges annually, 17.5 million inpatient days, and 30-day postdischarge costs of $238 726 per patient. Delirium is an acute disorder of attention and global cognitive function characterized by fluctuating symptoms occurring in the face of an underlying organic cause. As patients adapt to physiological stressors, neurotransmitter changes lead to electroencephalogram pattern changes. The ability to compensate for the chemical (neurotransmitter) imbalances is surpassed, causing the behavioral symptomatology we know as delirium. This article seeks to describe the pathophysiology behind the behavior core to the prevention and management of delirium. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 25% |
| United Kingdom | 1 | 25% |
| Unknown | 2 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 25% |
| Science communicators (journalists, bloggers, editors) | 1 | 25% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 98 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 17 | 17% |
| Student > Bachelor | 9 | 9% |
| Researcher | 8 | 8% |
| Student > Doctoral Student | 6 | 6% |
| Other | 5 | 5% |
| Other | 14 | 14% |
| Unknown | 39 | 40% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 26 | 27% |
| Nursing and Health Professions | 16 | 16% |
| Social Sciences | 4 | 4% |
| Biochemistry, Genetics and Molecular Biology | 3 | 3% |
| Immunology and Microbiology | 3 | 3% |
| Other | 8 | 8% |
| Unknown | 38 | 39% |