Title |
An insight into antimicrobial activity of the freshwater bryozoan Pectinatella magnifica
|
---|---|
Published in |
Natural Product Research, August 2015
|
DOI | 10.1080/14786419.2015.1068773 |
Pubmed ID | |
Authors |
Boris Pejin, Ana Ciric, Mladen Horvatovic, Tamara Jurca, Jasmina Glamoclija, Milos Nikolic, Marina Sokovic |
Abstract |
The antimicrobial activity of five crude extracts of the freshwater bryozoan Pectinatella magnifica (Leidy, 1851) was evaluated in vitro for the first time. P. magnifica acetone extract exhibited the highest antibacterial activity (minimum inhibitory concentrations (MIC) 0.004-0.350 mg/mL and MBC 0.007-0.500 mg/mL), while its methanol extract showed the most promising antifungal activity (MIC 0.03-0.12 mg/mL and MFC 0.06-0.25 mg/mL). Furthermore, at a concentration of 0.25 MIC, the methanol extract reduced biofilm formation of the bacterial strain Pseudomonas aeruginosa PAO1 in a considerable extent (59.14%). FTIR spectra of the most active extracts indicate the presence of carbonyl compounds, long-chain alcohols and/or sterols. According to the experimental data obtained, P. magnifica methanol extract may be considered as a good resource of novel natural products with potent antibiofilm activity against the bacterium well known for its resistance. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 33% |
Unknown | 2 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Serbia | 1 | 5% |
Unknown | 19 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Doctoral Student | 4 | 20% |
Student > Ph. D. Student | 3 | 15% |
Researcher | 3 | 15% |
Professor | 2 | 10% |
Student > Master | 2 | 10% |
Other | 2 | 10% |
Unknown | 4 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 4 | 20% |
Agricultural and Biological Sciences | 4 | 20% |
Immunology and Microbiology | 2 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 5% |
Arts and Humanities | 1 | 5% |
Other | 3 | 15% |
Unknown | 5 | 25% |