Realistic simulation of image formation in optical coherence tomography, based on Maxwell's equations, has recently been demonstrated for sample volumes of practical significance. Yet, there remains a limitation whereby reducing the size of cells used to construct a computational grid, thus allowing for a more realistic representation of scatterer microstructure, necessarily reduces the overall sample size that can be modelled. This is a significant problem since, as is well known, the microstructure of a scatterer significantly influences its scattering properties. Here we demonstrate that an optimized scatterer design can overcome this problem resulting in good agreement between simulated and experimental images for a structured phantom. This approach to OCT image simulation allows for image formation for biological tissues to be simulated with unprecedented realism.
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2018.
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#22,767,715
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Outputs of similar age from Biomedical Optics Express
#51
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