Left atrial (LA) strain (Ƹ) and Ƹ rate (SR) analysis by two-dimensional speckle tracking echocardiography (STE) is a novel way of functional assessment of LA.
We studied the impact of LA appendage (LAA) exclusion by LARIAT epicardial ligation on the mechanical function of LA by performing Ƹ and SR analysis before and after the procedure.
A total of 66 patients who underwent successful LAA exclusion were included in this study. Of 66, thirty-two patients had adequate paired data for Ƹ and SR analysis. SR during ventricular systole (LA-SRs) represents LA reservoir function and SR during early ventricular diastole (LA-SRe) represents LA conduit function. Ƹ and SR were determined from apical four and two-chamber views using electrocardiographic QRS as reference point. LA volume index (LAVI), as surrogate for LA remodeling, was measured from apical views.
The mean age of the patients was 70 (± 9.2) years. LAA ligation resulted in improved reservoir function [LA-SRs: 0.72; confidence interval (CI): 0.63 to 0.83 versus 0.81; CI: 0.73 to 0.98); p value = 0.043] and conduit function (LA-SRe: 0.74; CI: 0.67 to 0.99 versus 0.89; CI: 0.82 to 1.07; p value=0.025]. LAVI improved significantly with LARIAT (35.4; CI: 29.4 to 37. 2 versus 29.2; CI: 28.2 to 35.9 p value < 0.023).
LAA exclusion appears to improve mechanical function of LA and also results in reverse LA remodeling.
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 July 2018.
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