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Mendeley readers
Attention Score in Context
| Title |
Could Flavonoids Compete with Synthetic Azoles in Diminishing Candida albicans Infections? A Comparative Review Based on In Vitro Studies.
|
|---|---|
| Published in |
Current Medicinal Chemistry, January 2019
|
| DOI | 10.2174/0929867325666180629133218 |
| Pubmed ID | |
| Authors |
Marija Smiljković, Marina Kostić, Dejan Stojković, Jasmina Glamočlija, Marina Soković |
| Abstract |
Flavonoids are polyphenolic compounds with already confirmed various health benefits. This review will shed light on flavonoids as potential antifungals in Candida albicans infections. C. albicans is opportunistic pathogen able to cause serious health issues due to numerous virulence factors amplifying its pathogenicity. One of the most important virulence factors is Candida ability to form biofilms which are highly resistant to treatment with antifungal drugs; making diminishing of this pathogen even more challenging. This review will focus on current knowledge on individual flavonoid compounds potential to deal with C. albicans, with special turn on antibiofilm potential and insight into the mode of action. Majority of the commercial drugs for treatment of candidiasis belong to azole class, so the activity of flavonoids will be compared with the activity of newly synthetized azole compounds, as well as with azole drugs that are already on the market. This literature review will provide pros and cons for pushing future research towards exploring novel synthetic azoles or further examination of wide pallet of natural flavonoids. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 14 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 2 | 14% |
| Unspecified | 1 | 7% |
| Librarian | 1 | 7% |
| Student > Bachelor | 1 | 7% |
| Student > Doctoral Student | 1 | 7% |
| Other | 2 | 14% |
| Unknown | 6 | 43% |
| Readers by discipline | Count | As % |
|---|---|---|
| Immunology and Microbiology | 2 | 14% |
| Unspecified | 1 | 7% |
| Computer Science | 1 | 7% |
| Economics, Econometrics and Finance | 1 | 7% |
| Neuroscience | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 7 | 50% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 June 2018.
All research outputs
#20,663,600
of 25,385,509 outputs
Outputs from Current Medicinal Chemistry
#2,401
of 3,099 outputs
Outputs of similar age
#340,921
of 446,394 outputs
Outputs of similar age from Current Medicinal Chemistry
#91
of 171 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,099 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 446,394 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 171 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.