Unnecessary intervention and overtreatment of indolent disease are common challenges in clinical management of prostate cancer. Improved tools to distinguish lethal from indolent disease are critical.
We performed a genome-wide survival analysis of cause-specific death in 24,023 prostate cancer patients (3,513 disease-specific deaths) from the PRACTICAL and BPC3 consortia. Top findings were assessed for replication in a Norwegian cohort (CONOR).
We observed no significant association between genetic variants and prostate cancer survival.
Common genetic variants with large impact on prostate cancer survival were not observed in this study.
Future studies should be designed for identification of rare variants with large effect sizes or common variants with small effect sizes.
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 August 2023.
All research outputs
#2,877,608
of 34,545,128 outputs
Outputs from Cancer Epidemiology, Biomarkers & Prevention
#848
of 5,750 outputs
Outputs of similar age
#31,632
of 322,820 outputs
Outputs of similar age from Cancer Epidemiology, Biomarkers & Prevention
#9
of 50 outputs
Altmetric has tracked 34,545,128 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,750 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.6. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,820 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 50 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.
