This study aimed at comparing the fecal microbiota and metabolome of 26 healthy subjects before (HS) and after (HSB) two months of diet intervention based on the administration of durum wheat flour and whole-grain barley Pasta containing the minimum recommended daily intake (3 g) of barley β-glucans. Metabolically active bacteria were analyzed through pyrosequencing of the gene 16S rRNA and community-level catabolic profiles. Pyrosequencing data showed that Clostridiaceae (Clostridium orbiscindens, Clostridium sp.), Roseburia hominis, and Ruminococcus sp. increased while other Firmicutes and Fusobacteria decreased in HSB compared to HS fecal samples. Community-level catabolic profiles were the lowest in HSB. Compared to HS, cultivable lactobacilli increased in HSB fecal samples while Bacteroides, Porphyromonas and Prevotella, Enterobacteriaceae, total coliforms, and Pseudomonas, Alcaligenes and Aeromonas decreased. Metabolome analyses were performed using amino acid analyzer and gas-chromatography mass spectrometry-solid-phase micro-extraction. A marked increase of short chain fatty acids (SCFA) such as 2-methyl-propanoic acid, acetic, butyric and propionic acids was found in HSB with respect to HS fecal samples. Durum wheat flour and whole-grain barley Pasta containing 3% of barley β-glucans appeared to be effective in the modulation of the composition and the metabolic pathways of the intestinal microbiota, leading to an increased level of SCFA.
This research output has an Altmetric Attention Score of 90. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 January 2023.
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#581,551
of 33,087,078 outputs
Outputs from Applied and Environmental Microbiology
#184
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#6,218
of 302,733 outputs
Outputs of similar age from Applied and Environmental Microbiology
#6
of 163 outputs
Altmetric has tracked 33,087,078 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 21,660 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 302,733 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 163 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.
