Title |
Rosa canina L. – new possibilities for an old medicinal herb
|
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Published in |
Food & Function, January 2015
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DOI | 10.1039/c5fo00820d |
Pubmed ID | |
Authors |
Jelena Živković, Dejan Stojković, Jovana Petrović, Gordana Zdunić, Jasna Glamočlija, Marina Soković |
Abstract |
Health beneficial properties of Rosa canina species are mainly attributed to rose hips, while the leaves are usually discarded as waste. In the present study we investigated chemical constituents as well as antimicrobial and antibiofilm potential of R. canina methanolic leaf extract. Chemical analysis showed that dominant phenolic compounds are quercetin and isorhamnetin derivatives (isoquercetin and isorhamnetin-3-O-rutinoside). Among the tested bacteria, Pseudomonas aeruginosa and Salmonella typhimurium were the most susceptible to the activity of R. canina leaf extract with MIC and MBC values both 0.009 mg mL(-1). For most of the bacterial strains investigated the extract showed significantly higher activity compared to the used standard compounds streptomycin and ampicillin. Also the tested extract powerfully inhibited in vitro biofilm growth in Pseudomonas aeruginosa, Staphylococcus aureus, Leishmania monocytogenes and Escherichia coli at sub MIC-levels. With concentrations equal to 1/4 and 1/8 of MIC values biofilm growth of P. aeruginosa and E. coli was inhibited by 90%. The obtained results are significant for a wider and efficient use of R. canina leaves. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 17% |
United Kingdom | 1 | 17% |
Unknown | 4 | 67% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 3 | 50% |
Scientists | 2 | 33% |
Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Japan | 1 | 2% |
Serbia | 1 | 2% |
Unknown | 58 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 9 | 15% |
Student > Master | 7 | 12% |
Professor | 5 | 8% |
Student > Ph. D. Student | 5 | 8% |
Student > Bachelor | 4 | 7% |
Other | 8 | 13% |
Unknown | 22 | 37% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 15 | 25% |
Immunology and Microbiology | 3 | 5% |
Medicine and Dentistry | 3 | 5% |
Biochemistry, Genetics and Molecular Biology | 3 | 5% |
Nursing and Health Professions | 2 | 3% |
Other | 9 | 15% |
Unknown | 25 | 42% |