Brahmi (Bacopa monnieri) has been used by Ayurvedic medical practitioners in India for almost 3000 years. The pharmacological properties of Bacopa monnieri were studied extensively and the activities were attributed mainly due to the presence of characteristic saponins called "bacosides." Bacosides are complex mixture of structurally closely related compounds, glycosides of either jujubogenin or pseudojujubogenin. The popularity of herbal medicines and increasing clinical evidence to support associated health claims require standardisation of the phytochemical actives contained in these products. However, unlike allopathic medicines which typically contain a single active compound, herbal medicines are typically complex mixtures of various phytochemicals. The assay for bacosides in the British Pharmacopoeia monograph for Bacopa monnieri exemplifies that only a subset of bacosides present are included in the calculation of total bacosides. These results in calculated bacoside values are significantly lower than those attained for the same material using more inclusive techniques such as UV spectroscopy. This study illustrates some of the problems encountered when applying chemical analysis for standardisation of herbal medicines, particularly in relation to the new method development and validation of bacosides from KeenMind.
Pharmacology, Toxicology and Pharmaceutical Science
3
6%
Biochemistry, Genetics and Molecular Biology
3
6%
Environmental Science
2
4%
Agricultural and Biological Sciences
2
4%
Other
6
11%
Unknown
33
61%
Attention Score in Context
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2015.
All research outputs
#27,325,480
of 33,942,205 outputs
Outputs from Evidence-based Complementary & Alternative Medicine (eCAM)
#5,091
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Outputs of similar age
#222,214
of 303,163 outputs
Outputs of similar age from Evidence-based Complementary & Alternative Medicine (eCAM)
#148
of 224 outputs
Altmetric has tracked 33,942,205 research outputs across all sources so far. This one is in the 16th percentile – i.e., 16% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,618 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.4. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
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