| Title |
Nanoparticle-based monitoring of cell therapy
|
|---|---|
| Published in |
Nanotechnology, November 2011
|
| DOI | 10.1088/0957-4484/22/49/494001 |
| Pubmed ID | |
| Authors | |
| Abstract |
Exogenous cell therapy aims to replace/repair diseased or dysfunctional cells and promises to revolutionize medicine by restoring tissue and organ function. To develop effective cell therapy, the location, distribution and long-term persistence of transplanted cells must be evaluated. Nanoparticle (NP) based imaging technologies have the potential to track transplanted cells non-invasively. Here we summarize the most recent advances in NP-based cell tracking with emphasis on (1) the design criteria for cell tracking NPs, (2) protocols for cell labeling, (3) a comparison of available imaging modalities and their corresponding contrast agents, (4) a summary of preclinical studies on NP-based cell tracking and finally (5) perspectives and future directions. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | <1% |
| Singapore | 1 | <1% |
| Korea, Republic of | 1 | <1% |
| Germany | 1 | <1% |
| Canada | 1 | <1% |
| Bangladesh | 1 | <1% |
| Unknown | 134 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 26 | 19% |
| Researcher | 21 | 15% |
| Student > Master | 20 | 14% |
| Student > Bachelor | 16 | 11% |
| Student > Postgraduate | 7 | 5% |
| Other | 14 | 10% |
| Unknown | 36 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 19 | 14% |
| Agricultural and Biological Sciences | 16 | 11% |
| Physics and Astronomy | 13 | 9% |
| Medicine and Dentistry | 13 | 9% |
| Chemistry | 11 | 8% |
| Other | 26 | 19% |
| Unknown | 42 | 30% |