| Title |
Genes and environment in neonatal intraventricular hemorrhage
|
|---|---|
| Published in |
Seminars in Perinatology, October 2015
|
| DOI | 10.1053/j.semperi.2015.09.006 |
| Pubmed ID | |
| Authors |
Laura R. Ment, Ulrika Ådén, Charles R. Bauer, Henrietta S. Bada, Waldemar A. Carlo, Jeffrey R. Kaiser, Aiping Lin, Charles Michael Cotten, Jeffrey Murray, Grier Page, Mikko Hallman, Richard P. Lifton, Heping Zhang, on behalf of the Gene Targets for IVH Study Group and the Neonatal Research Network |
| Abstract |
Emerging data suggest intraventricular hemorrhage (IVH) of the preterm neonate is a complex disorder with contributions from both the environment and the genome. Environmental analyses suggest factors mediating both cerebral blood flow and angiogenesis contribute to IVH, while candidate gene studies report variants in angiogenesis, inflammation, and vascular pathways. Gene-by-environment interactions demonstrate the interaction between the environment and the genome, and a non-replicated genome-wide association study suggests that both environmental and genetic factors contribute to the risk for severe IVH in very low-birth weight preterm neonates. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 2% |
| Canada | 1 | <1% |
| Unknown | 110 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 19 | 17% |
| Student > Master | 11 | 10% |
| Researcher | 11 | 10% |
| Other | 10 | 9% |
| Student > Ph. D. Student | 6 | 5% |
| Other | 23 | 20% |
| Unknown | 33 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 47 | 42% |
| Agricultural and Biological Sciences | 7 | 6% |
| Veterinary Science and Veterinary Medicine | 3 | 3% |
| Nursing and Health Professions | 3 | 3% |
| Engineering | 2 | 2% |
| Other | 5 | 4% |
| Unknown | 46 | 41% |