| Title |
Helminth infection, fecundity, and age of first pregnancy in women
|
|---|---|
| Published in |
Science, November 2015
|
| DOI | 10.1126/science.aac7902 |
| Pubmed ID | |
| Authors |
Aaron D Blackwell, Marilyne A Tamayo, Bret Beheim, Benjamin C Trumble, Jonathan Stieglitz, Paul L Hooper, Melanie Martin, Hillard Kaplan, Michael Gurven |
| Abstract |
Infection with intestinal helminths results in immunological changes that influence co-infections, and might influence fecundity by inducing immunological states affecting conception and pregnancy. We investigated associations between intestinal helminths and fertility in women, using 9 years of longitudinal data from 986 Bolivian forager-horticulturalists, experiencing natural fertility and 70% helminth prevalence. We found that different species of helminth are associated with contrasting effects on fecundity. Infection with roundworm (Ascaris lumbricoides) is associated with earlier first births and shortened interbirth intervals, whereas infection with hookworm is associated with delayed first pregnancy and extended interbirth intervals. Thus, helminths may have important effects on human fertility that reflect physiological and immunological consequences of infection. |
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X Demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 1564 | 22% |
| China | 88 | 1% |
| United States | 34 | <1% |
| Korea, Republic of | 26 | <1% |
| Austria | 22 | <1% |
| Korea, Democratic People's Republic of | 17 | <1% |
| United Kingdom | 13 | <1% |
| France | 11 | <1% |
| Burkina Faso | 9 | <1% |
| Other | 188 | 3% |
| Unknown | 5098 | 72% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7036 | 100% |
| Scientists | 26 | <1% |
| Science communicators (journalists, bloggers, editors) | 6 | <1% |
| Practitioners (doctors, other healthcare professionals) | 2 | <1% |
Mendeley demographics
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | <1% |
| United Kingdom | 2 | <1% |
| Romania | 1 | <1% |
| Japan | 1 | <1% |
| France | 1 | <1% |
| Czechia | 1 | <1% |
| Unknown | 216 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 40 | 18% |
| Student > Ph. D. Student | 31 | 14% |
| Student > Bachelor | 30 | 13% |
| Student > Master | 27 | 12% |
| Other | 12 | 5% |
| Other | 43 | 19% |
| Unknown | 41 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 48 | 21% |
| Medicine and Dentistry | 31 | 14% |
| Biochemistry, Genetics and Molecular Biology | 20 | 9% |
| Social Sciences | 19 | 8% |
| Immunology and Microbiology | 17 | 8% |
| Other | 41 | 18% |
| Unknown | 48 | 21% |