Absolute lymphocyte count (ALC) has been identified as a prognostic factor in liver transplantation. We hypothesized that a lower ALC may be linked to poor outcomes in isolated intestinal/multivisceral transplantation (IIT/MVT). The aim of this study was to investigate the prognostic impact of ALC in IIT/MVT. A total 141 IIT/MVT patients were eligible for the study. Posttransplant ALCs (at 3, 6, and 12 months) were evaluated, and prognostic impact of trend of ALC during the first year was investigated. Of these 141 patients, 108 patients survived in the first year (one-year survivors). One-year survivors were categorized according to posttransplant ALC at each time point. When ALC was decreased throughout the first year (posttransplant persistent lymphopenia: <500/μL at 3, 6, and 12 months), patient survival (P<0.001, hazard ratio=5.09) and graft survival (P<0.001, hazard ratio=5.15) after the first year was significantly worse, and this remained to be an independent risk factor. Negative impact of persistent lymphopenia on patient and graft survival was significant regardless of type of intestinal graft. Infection leading to mortality occurred more frequently in the persistent lymphopenia group (43% vs. 24%). Trend of posttransplant ALC may be a strong predictive marker for long-term outcome in one-year survivors after IIT/MVT. This article is protected by copyright. All rights reserved.
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 May 2021.
All research outputs
#11,163,436
of 33,127,577 outputs
Outputs from Transplant International
#1,034
of 2,407 outputs
Outputs of similar age
#103,358
of 295,197 outputs
Outputs of similar age from Transplant International
#13
of 25 outputs
Altmetric has tracked 33,127,577 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 2,407 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.8. This one has gotten more attention than average, scoring higher than 56% of its peers.
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We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.
