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Circuit Robustness to Temperature Perturbation Is Altered by Neuromodulators

Overview of attention for article published in Neuron, September 2018
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  • Good Attention Score compared to outputs of the same age (65th percentile)

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Article details
Title
Circuit Robustness to Temperature Perturbation Is Altered by Neuromodulators
Published in
Neuron, September 2018
DOI 10.1016/j.neuron.2018.08.035
Pubmed ID
Authors
Abstract

In the ocean, the crab Cancer borealis is subject to daily and seasonal temperature changes. Previous work, done in the presence of descending modulatory inputs, had shown that the pyloric rhythm of the crab increases in frequency as temperature increases but maintains its characteristic phase relationships until it "crashes" at extremely high temperatures. To study the interaction between neuromodulators and temperature perturbations, we studied the effects of temperature on preparations from which the descending modulatory inputs were removed. Under these conditions, the pyloric rhythm was destabilized. We then studied the effects of temperature on preparations in the presence of oxotremorine, proctolin, and serotonin. Oxotremorine and proctolin enhanced the robustness of the pyloric rhythm, whereas serotonin made the rhythm less robust. These experiments reveal considerable animal-to-animal diversity in their crash stability, consistent with the interpretation that cryptic differences in many cell and network parameters are revealed by extreme perturbations.

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X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley demographics

Mendeley demographics

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Geographical breakdown
Country Count As %
Unknown 78 100%

Demographic breakdown

Readers by professional status
Readers by professional status Count As %
Student > Ph. D. Student 16 21%
Researcher 11 14%
Student > Bachelor 7 9%
Student > Master 6 8%
Student > Postgraduate 5 6%
Other 14 18%
Unknown 19 24%
Readers by discipline
Readers by discipline Count As %
Neuroscience 27 35%
Agricultural and Biological Sciences 12 15%
Engineering 5 6%
Physics and Astronomy 3 4%
Medicine and Dentistry 3 4%
Other 3 4%
Unknown 25 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 August 2021.
All research outputs
#7,267,105
of 25,385,509 outputs
Outputs from Neuron
#6,020
of 9,546 outputs
Outputs of similar age
#120,806
of 351,777 outputs
Outputs of similar age from Neuron
#136
of 154 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 9,546 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 33.2. This one is in the 36th percentile – i.e., 36% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 351,777 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.
We're also able to compare this research output to 154 others from the same source and published within six weeks on either side of this one. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.