Tumor fraction in cell-free DNA as a biomarker in prostate cancer

Overview of attention for article published in JCI Insight, November 2018

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We only captured one time point for a patient receiving daily RT to prostate and saw an increase in tumor fraction, but didn't see an increase during chemo or Ra-223. If we collected for cfDNA a few hours after chemo dose maybe we would see spike? http…

Tumor fraction in cell-free DNA as a biomarker in prostate cancer. https://t.co/Ghg1PjhKDy H/T @NCBI #radonc #PubMed

Small series, intriguing results using shallow WGS to track cfDNA tumor content in IO hyper- vs pseudo-progression BUT, tumor fraction can vary - prostate cfDNA shows variability in tumor fraction on maintenance hormonal tx @AtishChoudhury @JCI_insight…

RT @AtishChoudhury: "Tumor fraction in cell-free DNA as a biomarker in prostate cancer" now published in @JCI_insight https://t.co/FKKfh6bQ…

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