R-loop formation by dCas9 is mutagenic in Saccharomyces cerevisiae

Overview of attention for article published in Nucleic Acids Research, December 2018

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RT @DocDellaire: @joachimgoedhart Q? - Doesn't CRISPRi have a very clear possibility of inducing R-loop genome instability. see here: https…

@TrumanLab @AguzziTemp @NathalieJuYa Watch CRISPRi off-target from R-loop generation and DNA damage signalling. Going to be an obvious reviewer question, so controls will be important to assess. see: https://t.co/kKyKcgrJh5

@joachimgoedhart Q? - Doesn't CRISPRi have a very clear possibility of inducing R-loop genome instability. see here: https://t.co/kKyKcgrJh5 So depending on your question, you may have to try different approaches. One technique will not be appropriate…

R-loop formation by dCas9 is mutagenic in Saccharomyces cerevisiae. https://t.co/XKiDwVvrCf

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