A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site

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A GWAS sequence variant for platelet volume marks an alternative DNM3 promoter in megakaryocytes near a MEIS1 binding site - a recent publication by #GenMedCambridge speaker Prof Willem Ouwehand https://t.co/2x6DUj8SqS

Human megakaryocytes express dynamin 1 and an inactive dynamin 3 spliced variant, a SNP of which has been associated with platelet size. https://t.co/3OcbVtHeUG Questions remain on their role in human megakaryopoiesis.

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